Searchable abstracts of presentations at key conferences in endocrinology

ea0090oc9.1 | Oral Communications 9: Adrenal and Cardiovascular Endocrinology 2 | ECE2023

Identification of adrenocortical masses malignancy and aggressivity through radiomics: a pilot study

Tucci Lorenzo , Vara Giulio , Improta Ilaria , Leo Antonio De , Selva Saverio , Balacchi Caterina , Santini Donatella , Mosconi Cristina , Vicennati Valentina , Pagotto Uberto , Dalmazi Guido Di

Background: Adrenal lipid poor adenoma (LPA) and adrenocortical cancer (ACC) may overlap in computerized tomography (CT). Radiomics recently emerged as new tool for malignant behavior identification.Aim: To assess radiomics utility for identification of ACC and LPA in adrenocortical masses with unenhanced (UE) CT scan attenuation≥10 Hounsfield Unit (HU).Methods: We retrospectively enrolled 50 patients, 38 radiologically defin...

ea0056p61 | Adrenal cortex (to include Cushing's) | ECE2018

Histopathological characteristics of lipid-poor adrenal adenomas

Vicennati Valentina , Casadio Elena , De Leo Antonio , Mosconi Cristina , Nanni Cristina , Selva Saverio , Zavatta Guido , Rinaldi Eleonora , Pagotto Uberto , Santini Donatella , Di Dalmazi Guido

Background: Up to 30% of incidentally-discovered adrenal masses are lipid-poor adenomas (LPA). The clinical significance of LPA is poorly understood. The aim of the study was to investigate histopathological features of LPA and their association with radiological parameters.Methods: A total of 39 patients with radiological evidence of LPA were included. LPA was defined as an adrenal mass with pre-contrast Hounsfield units (HU) ≧10, associated wit...

ea0073pep11.4 | Presented ePosters 11: Adrenal and Cardiovascular Endocrinology | ECE2021

Computerized tomography texture analysis in pheochromocytoma: correlation with clinical, biochemical, and histopathological data

Di Dalmazi Guido , Vara Giulio , Leo Antonio De , Paccapelo Alexandro , Tucci Lorenzo , Vicennati Valentina , Selva Saverio , Balacchi Caterina , Santini Donatella , Minni Francesco , Pagotto Uberto , Golfieri Rita , Mosconi Cristina

Computerized tomography (CT) texture analysis (TA) provides a valuable amount of quantitative data on single voxels and their relationship in a target lesions, giving additional value to the CT scan. CTTA has been applied to several oncologic diseases. We aimed to correlate the data derived from CTTA of pheochromocytoma to clinical, biochemical and histopathological data in 30 consecutive patients. Pheochromocytoma was confirmed at histology. The CTTA was performed on unenhanc...

ea0093oc21 | Oral communication 3: Adrenal Tumors and Neuroendocrine Tumors | EYES2023

Identification of adrenocortical masses malignancy through radiomics: A pilot study

Tucci Lorenzo , Vara Giulio , Improta Ilaria , De Leo Antonio , Selva Saverio , Balacchi Caterina , Santini Donatella , Mosconi Cristina , Vicennati Valentina , Pagotto Uberto , Di Dalmazi Guido

Background: Adrenal lipid poor adenoma (LPA) and adrenocortical cancer (ACC) may overlap in computerized tomography (CT). Radiomics recently emerged as new tool for malignant behavior identification.Aim: To assess radiomics utility for identification of ACC and LPA in adrenocortical masses with unenhanced (UE) CT scan attenuation≥10 Hounsfield Unit (HU).Methods: We retrospectively enrolled 50 patients, 38 radiologically defin...

ea0099ep232 | Adrenal and Cardiovascular Endocrinology | ECE2024

The diagnostic dilemma of benign adrenal endothelial tumors: clinical, radiological, and pathological analysis of 20 rare cases

Coscia Kimberly , Mosconi Cristina , Tucci Lorenzo , Colombin Giacomo , Donnarumma Francesca , Balacchi Caterina , Selva Saverio , Di Dalmazi Guido , Vicennati Velentina , Pagotto Uberto , De Leo Antonio

Background: Adrenal endothelial tumors are mainly represented by adrenal cavernous hemangiomas (ACHs) and adrenal cystic lymphangiomas (ACLs). They are rare incidental findings, with about 160 cases of both ACHs and ACLS reported in the literature. They are usually unilateral, benign, non-functioning, and asymptomatic, although abdominal pain and life-threatening retroperitoneal hemorrhage may occur if tumor size increases. Radiological features often overlap with malignant ad...

ea0099ep326 | Adrenal and Cardiovascular Endocrinology | ECE2024

Radiomics for immunohistochemistry prediction in pheochromocytoma: a pilot study

Tucci Lorenzo , De Leo Antonio , Vara Giulio , Coscia Kimberly , Selva Saverio , Ricci Claudio , Alberici Laura , Balacchi Caterina , Santini Donatella , Vicennati Valentina , Pagotto Uberto , Mosconi Cristina , Tallini Giovanni , Di Dalmazi Guido

Background: Radiomics, or texture analysis, is gaining growing interest for its high prediction performances, mainly for clinical purposes. Radiomics application for pheochromocytoma immunohistochemistry (IHC) and molecular biology prediction is still unexplored.Aim: To evaluate radiomics ability to predict pheochromocytoma IHC.Methods: We retrospectively enrolled 38 pheochromocytoma who underwent surgery at Sant’Orsola-Malpig...

ea0099oc11.3 | Oral Communications 11: Adrenal and Cardiovascular Endocrinology | Part II | ECE2024

Prediction of adrenal masses nature through texture analysis and deep learning: Preliminary results from ENS@T RADIO-AI multicentric study

Tucci Lorenzo , Vara Giulio , Morelli Valentina , Menendez Torre Edelmiro Luis , Dischinger Ulrich , Markou Athina , Terzolo Massimo , Spyroglou Ariadni , Parazzoli Chiara , Carmen Aresta , Chiodini Iacopo , Rivas Diego , Gutierrez Alba , Schlotelburg Wiebke , Alexandraki Krystallenia , Puglisi Soraya , Improta Ilaria , De Leo Antonio , Selva Saverio , Alberici Laura , De Giglio Andrea , Pantaleo Maria Abbondanza , Balacchi Caterina , Mosconi Cristina , Vicennati Valentina , Pagotto Uberto , Di Dalmazi Guido

Background: Current parameters of conventional radiology have several limitations in defining the nature of adrenal masses. Radiomics, or texture analysis, has shown high diagnostic performance in recent pilot studies, although confirmatory studies are needed. Moreover, the effect of combination of radiomics with hormonal secretion on diagnostic performance is poorly explored.Aim: To evaluate the accuracy of radiomics in predicting adrenal masses nature ...